Kev kho mob titanium alloysTsis tsuas yog tsis muaj tshuaj lom, hnav, thiab tiv thaiv corrosion, tab sis kuj muaj biocompatibility zoo heev thiab ntuj muaj peev xwm ua ke nrog tib neeg cov pob txha, nws tuaj yeem siv los ua cov cog cog rau hauv tib neeg lub cev, thiab lwm yam, uas yog cov khoom siv kho mob zoo tagnrho. .
Marvel Universe's X-Men series films, Wolverine'stitanium alloytib neeg cov pob txha qhia lawv lub hwj chim thiab yog indestructible. Yog tias peb hloov kho titanium alloy rau hauv lub cev hauv lub ntiaj teb tiag lossis hloov peb cov pob txha nrog Ti pob txha, peb puas yuav muaj zog dua?
Thaum Lub Kaum Ib Hlis 25, 2021, Tianjin University, Hebei University of Technology, Hubei University, thiab lwm lub koom haum tshawb fawb tau luam tawm cov ntaub ntawv tshawb fawb muaj npe" Self-activated anti-infection implant" Hauv kev sib txuas lus xwm, Cov txiaj ntsig tau pom tiasTi6Al4V (ti6) titanium alloy cogHloov kho los ntawm HA / MoS2 txheej tau pom tias muaj cov kab mob tua kab mob siab rau Staphylococcus aureus thiab Escherichia coli, nws tuaj yeem ua kom cov pob txha rov tsim dua tshiab los ntawm kev txhawb nqa osteogenic sib txawv ntawm mesenchymal qia hlwb.
Hauv kev phais pob txha, nws yog ib qho nyuaj rau kev cog qoob loo nrog lub peev xwm zoo osteogenic thiab cov kab mob tua kab mob tib lub sijhawm. Kab mob kab mob thiab cov pob txha cov ntaub so ntswg kev koom ua ke nrog tus tswv tsev cov ntaub so ntswg ncua sij hawm rov qab los thiab nce qhov tshwm sim. Tus yuam sij rau kev cog qoob loo zoo yog nyob rau hauv kev sib txawv sai ntawm osteogenic ntawm osteoblasts ntawm qhov cog thiab kev tiv thaiv kab mob kab mob tib lub sijhawm.
Hydroxyapatite (HA) muaj cov pob txha zoo conductivity, nws tau siv dav hauv cov pob txha kev koom ua ke ntawm kev kho hniav thiab orthopedic implants. Ntxiv rau qhov zoo biocompatibility, molybdenum sulfide (MoS2) muaj lub cev thiab cov duab hluav taws xob tshwj xeeb, uas ua rau nws muaj peev xwm tiv thaiv kab mob gram-positive thiab Gram-negative.
Hauv txoj kev tshawb no, cov kws tshawb fawb tau npaj ob qho khoom siv saum toj no rau hauv HA / MoS2 txheej hloov khoTi6Al4V (ti6) coglos ntawm laser cladding thiab tshuaj vapor deposition (CVD). HA, / MoS2 txheej siv lub zog tsim los ntawm cov txheej txheem metabolic ntawm Staphylococcus aureus thiab Escherichia coli kom ua rau cov kab mob tua kab mob ntawm HA / mos2-ti6 yam tsis muaj zog ntxiv. nws yog tus kheej-activated txheej txheem tiv thaiv kab mob. Nyob rau tib lub sijhawm, nws tuaj yeem txhim kho qhov ciaj sia ntawm cov pob txha pob txha mesenchymal qia hlwb thiab txhawb kev sib txawv osteogenic ntawm cov pob txha pob txha mesenchymal qia hlwb los ntawm kev tswj hwm qib ntawm Ca2 +.
Lus Cim: HA / MoS2 txheej tuaj yeem tiv thaiv kab mob thiab txhawb cov pob txha rov tsim dua tshiab
